DECREASED EXPRESSION AND IMPAIRED FUNCTION OF MUSCARINIC ACETYLCHOLINE RECEPTORS IN THE RAT HIPPOCAMPUS FOLLOWING TRANSIENT FOREBRAIN ISCHEMIA

Decreased expression and impaired function of muscarinic acetylcholine receptors in the rat hippocampus following transient forebrain ischemia

In this study, we investigated whether transient cerebral ischemia affects the function and Blanks molecular expression of specific muscarinic cholinergic receptors.Our results show that in contrast to the GABA-B and A1 adenosine receptor systems, the ability of muscarinic receptors to attenuate evoked excitatory responses at vulnerable CA1 synapse

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Association between acute liver injury & severity and mortality of COVID-19 patients: A systematic review and meta-analysis

Background: Acute liver injury (ALI), a complication often seen in COVID-19 patients, can lead to severe liver damage, multi-organ failure, acute vascular events, and can potentially escalate to patient mortality.Given this, we initiated a meta-analysis to investigate the correlation between ALI and adverse outcomes in COVID-19 patients.Methods: We

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